Wild blueberries may protect DNA from damage
Juice made from wild blueberries may reduce oxidative damage to DNA by around 3% and decrease the risk of cardiovascular and degenerative diseases, suggests new data.
DNA damage in 18 male volunteers was reduced from 12.5 to 9.6% following daily consumption of an anthocyanin-rich blueberry juice for six weeks, according to findings published in the European Journal of Nutrition.
“Under our experimental conditions, the wild blueberry drink reduced the level of oxidized DNA bases and increased the protection from the ex vivo [hydrogen peroxide] H2O2-induced DNA damage,†wrote researchers from Universita degli Studi di Milano (Italy) and The University of Maine (USA).
“These results were particularly evident in the group of smokers/ex-smoker subjects with respect to non-smokers.
“This effect on DNA damage may be dependent on phytochemicals present in the wild blueberry drink that can exert a direct protective effect against oxidative insult by scavenging reactive oxygen species in blood.â€
The wild blueberry juice provided daily doses of anthocyanins of 375 milligrams.
Study details
The researchers recruited men with an average age of 48 and with at least one risk factor for cardiovascular disease (CVD) to participate in their six week study. Participants consumed a daily glass of wild blueberry juice or placebo for six weeks.
Results showed that DNA damage in white blood cells was reduced from 12.5 to 9.6% following daily consumption of the blueberry juice for six weeks, while no changes were observed in the placebo group.
In addition, when blood cells were exposed to H2O2, DNA damage was reduced from 45.8 to 37.2 % in the juice group. Again, no changes were observed in the placebo group.
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