Vitamin B3 Found In Milk May Result In Substantial Health Benefits
A new study from researchers at the Weill Cornell Medical College and the Swiss Polytechnic School in Lausanne reveals that a unique form of vitamin B3 that occurs in small quantities in milk produces substantial health benefits in high doses in mice.
According to the June issue of Cell Metabolism, high doses of the niacin-related vitamin precursor nicotinamide riboside (NR) prevent obesity in mice that have been fed a fatty diet. Furthermore, it increases muscle performance and energy expenditure, whilst preventing the development of diabetesdevelopment without any side effects.
The mouse experiment was designed by research leader Dr. Johan Auwerx and his Swiss team, whilst the team from Weill Cornell Medical College, who played leading role in uncovering the biological story of NR, found a method to administer sufficient doses of NR to the animals.
Dr. Anthony Sauve, a pharmacologist and organic chemist and associate professor of Pharmacology at Weill Cornell Medical College, remarked: “This study is very important. It shows that in animals, the use of NR offers the health benefits of a low-calorie diet and exercise – without doing either one.”
Dr. Sauve, a pioneer and leader in investigating how NAD can signal adaptation in cells and in physiology, invented a simple method to efficiently synthesize NR on a large scale, was the first scientist to demonstrate that NR elevates nicotinamide adenine dinucleotide (NAD) levels in mammalian cells. NAD plays a key role in energy metabolism.
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