Choline intake linked to lethal prostate cancer risk

A new study in the American Journal of Clinical Nutrition suggests that eating too much choline-rich foods such as meat, milk and eggs may increase risk of lethal prostate cancer. It is a possibility, but the study is not a trial and a causal relationship has not been established.

Erin L. Richman of Harvard School of Public Health, Boston, MA and colleagues conducted the study and found men in the highest quintile of choline intake were at 70 percent increased risk of lethal prostate cancer, compared with those in the lowest quintile.

Meat, milk and eggs, which are high in choline, have been associated with risk of lethal prostate cancer although not all studies are consistent. The current study was intended to examine whether intake of choline is associated with the risk of lethal prostate cancer.

For the study, the researchers analysed data from 47,896 men in the Health Professionals Follow-up Study to determine whether an association exists between intake of choline and risk of lethal prostate cancer. They also evaluated how the intake of choline affects the survival rate among 4,282 men with diagnosed nonmetastatic prostate cancer during the follow-up.

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